Question
Explain what is a base line?
Answers
Base line is nothing but the detectors response to the mobile phase.(gc,hplc) 
Base line should be stable to start a run. 
Un stabilized base line is called as base line noise. 
Base line noise is of many types.. 

Cyclic base line 
Synchorinise noise 
Asynchorinise noise 
Base line drift 
Spikes 
Negative peaks 
No peaks

Base line noise is attributed due to mobile phase,sample, system problems.leaks in the system,temperature variations in lab etc..   Your Comment




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