The anthocyanins are generally soluble in water. But, the polyphenolic structure adds a measure of hydrophobic character which gives the anthocyanin solubility in organic solvents. The combination of this polar and hydrophobic nature makes aqueous/organic solvent mixtures the ideal solvent. Normally, the organic solvent content varies from 50% to 100% of the mixture. The organic solvent is usually methanol and ethanol but many other solvents have also been used such as acetone or acetonitrile.   _{Your Comment}